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About iHuman Institute<\/strong><\/p> \n

The iHuman Institute is an international research effort to improve our understanding of human health through human cell signaling research. The Institute is focused on the basic and applied science of human cell signaling, integrating multiple tools for scientific discovery, and bringing together leading researchers throughout the world. iHuman Institute has research groups in chemical and cell biology, chemistry, computational chemistry, imaging, structural biology, system biology, and translational biology. The iHuman Institute is located on the campus of ShanghaiTech University in Shanghai, China. For more information, visit www.ihuman-institute.org<\/a>.<\/p> \n

RuiYi's iCAPS platform, the leading GPCR drug discovery platform, can isolate and present functional GPCRs in their correct confirmation to identify selective monoclonal antibody inhibitors or activators with great specificity for more effective therapeutics. GPCRs are a valuable class of drug targets but have been largely unexplored because of difficulty isolating GPCRs in the correct conformation and functional form, as well as finding drug candidates that have the necessary specificity for therapeutic intervention. RuiYi has developed a series of technologies, termed intermembranous Conformation Antigen Presenting System or iCAPS, that enable the presentation of purified, isolated, functional and conformationally correct GPCRs optimized for generation of antibodies and other biologic modulators.<\/p> \n

About RuiYi<\/strong><\/p> \n

RuiYi is focused on the discovery and development of novel biologic therapeutics that meet medical and commercial needs for China's patients and healthcare system and that have the potential to be disruptive globally. In addition to RYI-008, RuiYi has a growing pipeline of monoclonal antibodies from its internal discovery efforts utilizing a series of the Company's technologies, including the iCAPS (intramembranous Conformation Antigen Presenting System). Targets include a select subset of G protein coupled receptors (GPCR), where specificity in binding is critical but has proven difficult to achieve with small molecule modulators. RuiYi's executive management team has offices in La Jolla, California, and RuiYi's discovery efforts and research facility are located in in the Zhangjiang Hi-Tech Park in Pudong, Shanghai, China. For more, visit www.ruiyibio.com<\/a>.<\/p>"]; $("#dvExtra").html(content_array[0]);})();