GUANGZHOU, China, April 19, 2021 /PRNewswire/ -- At this year's American Association for Cancer Research (AACR) Annual Meeting 2021 (April 10-15), molecular diagnostic company AnchorDx presented a poster (Poster 2610) unveiling its Aurora 2.0 study results. The poster introduced the company's upgraded one-tube methylation sequencing technology for gastric cancer (GC) screening.
According to the study, Aurora 2.0's overall performance (AUC) in GC screening is 97.4%, achieving an overall sensitivity of 86.7% and a stage I sensitivity of 87.5% at a pre-defined specificity of 99%. In addition to superior sensitivity and specificity features, Aurora 2.0 retains its original advantages such as low cost and short turnaround time. In China, the incidence and mortality of gastric cancer rank second (10.5%) and third (12.4%), respectively. The prevention and treatment of GC have been a major challenge due to a lack of effective screening methods. Thus, a blood-based Aurora gastric cancer screening renders significant clinical value.
Methodology
Results
According to the company's current R&D results, the Aurora-based multi-cancer classifier has been proven to deliver high accuracy and efficiency in early cancer detection. A larger independent cohort comprised of four major cancers (Lung, breast, colorectal and gastric) and a finalized model of esophagus cancer are expected to be completed in the first half of 2021.
About AnchorDx
Founded in 2015, AnchorDx is a world-leading developer of cancer screening and early detection solutions based on methylation NGS technology. AnchorDx strives to revolutionize single/multi/pan-cancer early screening, detection technologies, and products. The current product pipeline encompasses more than 70% of high-incidence cancers. In addition, AnchorDx has a proprietary big data and artificial intelligence platform designed for early lung cancer screening, diagnosis, and treatment.